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Wang and his team developed new drugs based on furosemide to target both A accumulation and brain inflammation, which are key factors contributing to AD (112)

However, in the other two studies, there was not significant improvement with lanicemine compared with placebo at 24 h in people with treatment-resistant MDD (NCT00491686) [94] nor at week 6 in people with MDD and inadequate response (NCT01482221)