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In summary, AS-IV can target the downregulation of cAMP/PKA pathway activity and inhibit its induction of RTEC pyroptosis and EMT, thereby alleviating renal fibrosis (160)

It aids in minimizing the effects of free radicals and impurities on the skin which reduces the negative effects of time and the environment

In a broader context, our findings suggest that non-canonical pathways of Cu uptake may be activated under certain physiological and pathological conditions

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Contrera KJ, Huang AT, Shenson JA, Tang C, Roberts D, Myers JN, Weber RS, Lai SY, Williams M, El-Hallal M, Jacob D, Zafereo ME