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Aromatic side chain Tyr212 is essential for SnCE1 AcT activity AlphaFold3 structure prediction of the complex structure of monomeric SnCE1 with coenzyme A (CoA) (pTM+ipTM: 0.78 + 0.80) suggests the validity of the model and binding of CoA to S1 in SnCE1 being possible without the presence of an extended VR-3 in SnCE1 (Fig

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contributed to writing the manuscript

The transcriptional regulation of DNL is mainly orchestrated by two key transcription factors: sterol regulatory element-binding protein 1c (SREBP1c) and carbohydrate regulatory element-binding protein (ChREBP) (Sanders and Griffin, 2016)

Pigment-correcting serum Pigment-correcting serum was recently reformulated to address the multiple pathways involved in the induction of hyperpigmentation