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*Correspondence: Mary Kathryn Sewell-Loftin [email protected] This article was submitted to Cardiovascular Biologics and Regenerative Medicine, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In this respect, it is important to consider that the molecular granularity that impacts transcription of AR target genes and is recognized today is likely still an underestimation (Fig