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The measurable weight-loss effect in research is modest and shows up most clearly when L-carnitine is combined with a calorie-appropriate diet and exercise

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Under cystine deprivation stress, GBM cells can upregulate GGT1 expression and utilize alternative pathways to maintain GSH homeostasis, thereby preventing the occurrence of ferroptosis ( 5.4 Safety and selectivity challenges in ferroptosis therapy Achieving tumor-specific ferroptosis induction while preserving normal tissues, particularly brain function, is a core challenge for clinical translation

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