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NEW TO THIS EDITION 1,500 full-color clinical photographs (more than twice the amount found in the previous edition) New chapter template Clinical Summary clinically relevant observations on differential diagnosis Emergency Department Treatment and Disposition a brief overview of need-to-know diagnostic guidelines and recommendations Clinical Pearls instructive tips and insights on specific aspects of conditions which are difficult to find in other texts Four new chapters that enhance the book s hands-on value: Tropical Medicine reflects an increased emphasis on global access to healthcare and easier patient travel Toxicology features an up-to-date, authoritative review of how to diagnose and treat selected toxicological emergencies ECG Abnormalities presents turnkey insights into the rapid recognition of pathological ECG s, highlighting the electrocardiographic characteristics of each featured clinical problem Airway Procedures includes essential information that guides, improves, and expedites the management of airway emergencies

TPGS-NO prolonged NO release in tumors, leading to increased angiogenesis and apoptosis (Figure 3) while inhibiting DNA repair post-radiation

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CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions