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Not intended for human or veterinary use, consumption, administration, or diagnostic purposes

the predicted binding mode of 1j indicates the C5-amino substituent forms hydrogen bonding interaction with the carboxylic backbone of the Ser201 residue and a hydrophobic bonding with the Ser213 residue unlike the NCA amide group that is in hydrogen bonding distance from with the NNMT Ser213 residue

Some of the side effects may be uncommon yet severe

These investigations provide insight into mechanisms that regulate energy expenditure, adipocyte function, and metabolic homeostasis

Their appeal lies in being a non-stimulant, nutrient-based support option