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People may be deficient in vitamin B12 if they dont eat animal products, or if their body does not absorb it well naturally

doi: 10.1016/j.acthis.2023.151997

10.1126/science.1100747

Acknowledgments The authors would like to acknowledge the Committee of National Natural Science Foundation of China (30560042, 81160161, 81360198, and 82160255), Education Department of Jiangxi Province (GJJ13198 and GJJ170021), Jiangxi provincial department of science and technology (20142BBG70062, 20171BAB215022, and 20192BAB205043), and Health and Family Planning Commission of Jiangxi Province (20181019, 202210002, and 202310119) for supporting this work

Ignoring the signs of deficiency: If you have bleeding gums or constantly dry skin, your body will use the supplement to fix those internal symptoms of low vitamin c first, before sending it to your skin