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Prebiotics orchestrate probiotic proliferation enhancement, systematically inhibiting uremic toxin biosynthesis within colonic environments while dramatically amplifying SCFA generation cascades, thereby establishing intricate synergistic mechanisms specifically engineered to combat CKD-associated nephropathic processes (Tsai et al., 2019)

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Consequently, any impairment of liver function, particularly in individuals with chronic liver disease, can lead to substantial alterations in iron regulation [3, 29]

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Mena S, Ortega A, Estrela JM: Oxidative stress in environmental-induced carcinogenesis