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As a result, large immunogenic gluten peptides, such as the well-known 33-mer peptide from -gliadin, persist in the gut lumen and mucosa after gluten ingestion (De Re et al

Conclusions Oxidative damage plays a pivotal role in disrupting the BBB, significantly contributing to the pathogenesis of neurodegenerative diseases by promoting neuroinflammation and neuronal injury through the influx of blood-derived proteins into the brain (Figure 4)

Stronger associations have been observed in women and in older age groups, underscoring the growing public health relevance of schizophreniadementia comorbidity (14, 15)