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PDSS2 also attenuated ferroptosis in HCAECs by activating the antioxidant factor NF-E2-related factor 2 (Nrf2) (Yang et al., 2021)

One such mechanism involves cysteinyl-tRNA synthetase (CARS), an enzyme canonically known for catalyzing the synthesis of cysteinyl-tRNA [41]

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Another theory thought to be associated with the development of ASD is the leaky gut hypothesis. This hypothesis posits that increased intestinal permeability in children with ASD may lead to enhanced absorption of agents within the gut lumen, which could contribute to the development of the disorder