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Moreover, it has been previously shown that GPX4 overexpression in cancer cells inhibits RSL3-mediated ferroptosis, whereas GPX4 deletion increases susceptibility to ferroptosis [22]

Mitophagy receptor FUNDC1 is regulated by PGC-1/NRF1 to fine tune mitochondrial homeostasis

No common side effects seen Consult your doctor if you experience any unusual symptoms

The ability of arsenic, specifically arsenic trioxide, to treat acute promyelocytic leukaemia has radically changed the perception of this poison and has been the main factor for the re-emergence of this candidate to Western medicine for the treatment of leukaemia and other solid tumours

Patients with CKM experience a spectrum of functional and structural cardiac abnormalities, eventually leading to diastolic dysfunction, myocardial fibrosis, and left ventricular (LV) hypertrophy [40]