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Conversely, impaired autophagy can exacerbate apoptosis and further intensify ER stress, contributing to the development of IBD

10.1080/15384101.2015.1068479 59 JiangL.KonN.LiT.WangS

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These changes further disrupt antioxidant defense mechanisms in the brain, exacerbating age-related pathologies, including neurodegeneration and memory impairments (Singh and Kumar, 2008