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1 10 4 cells were plated in 24-well plate and treated with TMZ and ferroptosis modulators for 72 or 120 h

PMID: 10501046

The understanding of this mechanism was later derived from a separate study involving mice.

346,347,348 The first is the exogenous route, in which the NADs are directly introduced into the obtained exosomes via electroporation, co-incubation, sonication, extrusion, and freeze-thaw cycling