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[DOI] [PMC free article] [PubMed] [Google Scholar] Yang WS, SriRamaratnam R, Welsch ME

Kong X, Gao J

For instance, the C225 monoclonal antibody has been used to target EGFR, a protein commonly overexpressed in oral cancer cells (Ge et al

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This shifts dosage control from mg of garlic to biologically effective dose. By combining rigorous chemical standardization, GMP-like manufacturing, and biomarker-based PK/PD calibration, it is feasible to overcome natural-source variability and define reproducible, clinically meaningful OSC dosestransforming OSCs from variable botanicals into pharmaceutical-grade agents