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Soluble Uric Acid Triggers the NLRP3 Inflammasome in a Mitochondrial ROS-Dependent Manner In an attempt to address the mechanisms by which sUA promotes NLRP3 inflammasome activation, we analyzed mitochondrial ROS production by staining cells with the mitochondrial-targeting fluorescent probe MitoSOX 53

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This decline correlates directly with reduced collagen production, slower wound healing, increased inflammation, and the visible signs of skin aging wrinkles, sagging, dullness, and loss of elasticity

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