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For example, silencing both NaPDR1 and NaPDR1-like in wild tobacco following Alternaria alternata infection compromised resistance, impaired growth, and increased foliar disease severity, confirming PDR transporters function in biotic stress responses (Xu et al., 2018)

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Similar results were produced in another study using undifferentiated hBECs exposed to PM, showing reduced inflammation through the p38/NF-B/NLRP3 pathway [20]