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It also has been described that -glutamylcysteine, the intermediate of GSH biosynthesis, is able to act as a Gpx1 cofactor in mitochondrial H 2 O 2 detoxification, mimicking the physiological properties of GSH (Quintana-Cabrera et al., 2012)

Its unnecessary to cycle off either compound

Dias Pinto, and R

Additionally, nitrous oxide-based anesthesia has been observed to elevate plasma Hcy levels and significantly impair endothelial function in patients undergoing noncardiac surgery, potentially increasing the risk of postoperative cardiovascular morbidity [36]