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The GluN subunits contain an extracellular amino-terminal domain (ATD), a ligand-binding domain (LBD), a transmembrane domain (TMD), and an intracellular C-terminal domain (CTD)

Derbyshire (2013)

Zinc deficiency promotes the production of IL-1 by increasing the accessibility of the IL-1 promoter, which possibly results in a constitutive IL-1 production even in the absence of danger signals

11201ES03, Yeasen, Shanghai, China) on a CFX384 real-time PCR system (Bio-Rad Laboratories, Hercules, CA, USA)

FA might be implicated in cancer development in patients carrying mutations in the tumour suppressor BRCA2, and in the onset of some human conditions such as Fanconi Anaemia