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Anakinra is a recombinant, non-glycosylated human IL-1 receptor antagonist, which has a highly safe profile and large dosages have been utilized even in patients with severe viral illnesses, such as EBV, H1N1, and Ebola [83]

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Intramuscular administration of cyanocobalamin in patients with pernicious anemia and low serum levels of vitamin B12 (three to ten times lower than reference level) increases the number of CD8+ and decreases CD4/CD8 ratio back to normal [37]

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Used in situations when multiple-dose vials are required, because the bacteriostatic agent prevents bacterial contamination during repeated entries

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