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doi: 10.1002/vms3.692 36 PiantoniPWangPDrackleyJKHurleyWLLoorJJ

Its appeal comes from stability and breadth: BPC-157 stays intact in gastric acid, where most growth-factor peptides break down, and animal studies link it to repair across skin, muscle, tendon, ligament, bone, nerve and the gastrointestinal tract

It also prevents the migration and adhesion of RPE cells involved in the formation of epiretinal membranes in AMD, through inhibition of PDGF-beta receptor activity and downstream signaling pathways [90]

In vitro studies provide further mechanistic insight, showing that lithium enhances mitochondrial function, supports oxidative balance, and prevents apoptosis through mechanisms involving cytochrome c regulation, Bcl-2 modulation, and preservation of complex I activity

PAS staining Periodic Acid-Schiff (PAS) staining was performed to identify goblet cells in the colonic tissue of piglets