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Description

The evidence indicates that ferroptosis is closely related to the pathological process of RP

We found that the deficiency of deglutamylases CCP1 or CCP5 leads to a highly reduced and diffused signal of LCA5, suggesting that the bulge region is lost, thus preventing membrane disc formation and presumably causing photoreceptor death (Figs

This might explain the wide variation in the CQD sizes observed in certain precursors

Methods : A systematic review of the literature was performed in alignment with the PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses)