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However, one of our patients who had the more severe CVS (1 crisis per week) improved his BMI from -2.4SD to -0.3SD after one year of treatment indicating that or some individuals, the nutritional aspect of CVS can be a real task which must be taken into account

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The resulting .pdb files were processed in AutoDock Tools, where Gasteiger charges were applied, and the structures were converted to pdbqt format for docking studies 68

This is seen in medical conditions such as rheumatoid diseases, cancer, and allergic reactions (35)