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Additionally, advanced cirrhosis patients often experience abdominal symptoms such as pain and reflux, and are sarcopenic, a factor independently associated with mortality (13)

Overall, vitamins D and B12 are essential for general health, and their deficiency can impact thyroid health specifically, due to the resulting immune system dysregulation, favoring organ-specific autoimmunity in predisposed subjects

Enhancing inhibitory signals in the pain pathway: vitamin B12 has been found to increase the effectiveness of norepinephrine and 5-hydroxytryptamine as inhibitory signals in the pain pathway, resulting in reduced pain perception

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Dionisi-Vici, C