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In preclinical studies, it inhibited proliferation of a broad range of tumor cell lines (cell IC50 6.2 nM to 4.3 M) and inhibited HUVEC growth in response to HGF and VEGF as an in vitro model of angiogenesis [116]

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The volcano plot was performed to visualize the predictive component loading and identify significantly altered metabolites by their content variation (Difference) and statistical significance (log 10 P -value)

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