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This is related to copper sensitivity in some patients

J Biochem Mol Toxicol 3:e23203 Docrat TF, Nagiah S, Naicker N, Baijnath S, Singh S, Chuturgoon AA (2020) The protective effect of metformin on mitochondrial dysfunction and endoplasmic reticulum stress in diabetic mice brain

This may impact not only the companys valuation per share but also voting control, depending on the quantity and price of the new shares in relation to the existing ones