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Specifically, thiamine is important for glucose metabolism [51] and type 2 diabetics have been observed to have lower-than-average thiamine levels, suggesting that some degree of thiamine deficiency may play a role in the onset of diabetes

Also, this research was designed to investigate the impact of EDD on the protein expression of CYP450 isozymes [CYP 11A1, 21A2 and 19C] and the activity of both 17-Hydroxysteroid Dehydrogenase and 17-ketosteroid reductase, which are involved in steroid hormone synthesis since no previous studies have been performed

Previous MRS studies have used the ratio of excitatory (Glu) and inhibitory (GABA) neurotransmitters as a proxy index of E/I balance in cortical networks and recent work found a positive correlation between GABA and Glx in medial parietal cortex 54 , consistent with electrophysiological evidence 55

Rubello, P