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These studies suggest that the metabolic contributions of intracellular ATP have significant impacts on acquired drug resistance against chemotherapeutic drugs

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Kern JK, Geier DA, Deth RC, Sykes LK, Hooker BS, Love JM et al (2017) Systematic assessment of research on autism spectrum disorder (ASD) and mercury reveals conflicts of interest and the need for transparency in autism research

Turning to miRNAs roles in immunotherapy, it is of note that the antitumor efficacy of inhibiting CTLA-4 and PD-1 receptors and their corresponding ligand, PD-L1, has been reduced for a couple of reasons