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Increasing antioxidant intake has been shown to deplete OS, accordingly, creating an energy crisis for preneoplastic cells, resulting in suppression of cell growth and activation of cell death pathways to impart chemopreventive effect during cancer progression pathway [279]

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Elevated Ca 2+ levels in the mitochondrial matrix result in upregulation of ATP synthase and other components of the oxidative phosphorylation machinery in order to meet the increased ATP demand [133]

166 , 167 , 168 The molecular defect in these cases has been associated with different missense mutations

Liraglutide shares 97% similarity with GLP-1 and is characterized by its prolonged action in the body [39]