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Dihexa was administered intraperitoneally (i.p.) at 0.5 mg/kg in phosphate buffered saline (PBS) on alternate days, commencing 15 days post-surgery and continuing through day 48, with control animals receiving PBS alone

Abstract Protein tyrosine phosphatases regulate signal transduction pathways involving tyrosine phosphorylation 1 and have been implicated in the development of cancer, diabetes, rheumatoid arthritis and hypertension 2

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