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Exp Mol Med 39 : 756768 Lowry MH, McAllister BP, Jean JC, Brown LA, Hughey RP, Cruikshank WW, Amar S, Lucey EC, Braun K, Johnson P, Wight TN, Joyce-Brady M 2008 Lung lining fluid glutathione attenuates il-13-induced asthma

Acetyl-L-carnitine (ALCAR) (500mg per serving) ALCAR is a mitochondrial cofactor that plays a key role in cellular energy production and nerve cell maintenance.48 Its been shown to improve nerve regeneration and reduce neuropathic pain in people with diabetes, particularly at daily doses of 1,0002,000mg.49 While Nerve Defend provides a lower dose, combining ALCAR with ALA and NAC may enhance its therapeutic effect.63 64 N-acetylcysteine (NAC) (600mg per serving) NAC is a precursor to glutathione one of the bodys most important antioxidants.50 In the context of diabetic neuropathy, oxidative stress plays a major role in nerve damage

doi: 10.3389/fmicb.2021.658292 175 XuL.LiuB.HuangL.LiZ.ChengY.TianY.et al

Similarly, VEGF and intercellular adhesion molecule-1 (ICAM-1) were inhibited

Flannagan, R