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Ch.2.2.2.1 (eds Picardo, M

Cells were incubated in medium containing 13 C 6 -glucose

Values are expressed as means SD at least three independent experiments

These Pt-mDNA adducts impair mitochondrial DNA replication and transcription, leading to altered protein synthesis and functional errors of the respiratory chain (Canta et al., 2+ signaling (Canta et al., 1985)