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1.3 Absorption of dietary glycotoxins and their dual biological impacts Besides endogenous RCS and AGEs, exogenous glycation products, derived from the regular diet, contribute substantially to the total AGE burden in the human organism (Figure 3)

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Blood 106:4445, 2005

Peptides rich in non-polar residues such as tryptophan, phenylalanine, isoleucine, leucine, valine, and methionine present a high proportion of hydrophobic surface area