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(2024) 13:e240221

In the GHK-Cu complex, the Cu (II) ion is coordinated by the nitrogen from the imidazole side chain of the histidine, another nitrogen from the alpha-amino group of glycine, and the deprotonated amide nitrogen of the glycine-histidine peptide bond (Figure 1)

While its not always harmful, in some cases, it can indicate an underlying health condition, such as liver or kidney dysfunction, that warrants attention 3 , 5

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Effects of selenium supplementation in patients with mild cognitive impairment or alzheimers disease: A systematic review and meta-analysis