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AOD-9604 Research Applications & Key Findings Metabolic and Obesity Research Weight Loss and Fat Reduction Studies Initial clinical trials in obese adults showed promising results, though later studies revealed limitations

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Therefore, although some oligonucleotide products targeting NNMT have shown effectiveness in vitro and in animal experiments, to date, no oligonucleotide products targeting NNMT have been used in clinical trials

A confirmed, untreated B12 deficiency can contribute to nerve symptoms and anemia over time, and for older adults the balance problems that severe deficiency can cause may raise the risk of falls

NNMT Inhibition At the core of 5-Amino-1MQs effects is its ability to inhibit nicotinamide N-methyltransferase (NNMT) , an enzyme found in multiple tissues including fat cells, liver, and muscle