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Science 333 , 843850 (2011)

FIGURE 1 TABLE 1 Table of shared pathogenic mechanisms in PD and metabolic dysfunction

Initially, it promotes mitochondrial biogenesis by activating peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), which enhances the expressions of genes involved in mitochondrial function and oxidative phosphorylation [159]