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TCR T cell receptor T cell activation can be said to be mediated by two distinct classes of cytoplasmic signaling sequence: those that initiate antigen-dependent primary activation through the TCR (primary cytoplasmic signaling sequences) and those that act in an antigen-independent manner to provide a secondary or co-stimulatory signal (secondary cytoplasmic signaling sequences)

(2013) have documented that high NaS levels led to radical superoxide upregulation and apoptosis of spiral ganglion neurons in vitro

Escherichia coli (ATCC 25922) was used as a control in the sensitivity test