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doi: 10.1111/1750-3841.15598 491 YangRShanSZhangCShiJLiHLiZ

Despite their proliferative arrest, senescent cells exhibit a metabolically active state characterized by an altered glycolytic flux, perturbed lipid homeostasis, mitochondrial dysfunction, and a disrupted nicotinamide adenine dinucleotide (NAD +) redox balance, all of which contribute to vascular damage

Yoshiji, R., Hirose, A., Tanaka, K

Research shows that nicotine activates nAChRs on dopaminergic neurons, which are crucial for regulating neurotransmitter release and neuronal excitability (Quik et al., 2008)

This is why glutathione, because it replenishes the bodys own levels, has become a standard practice in the integrative treatment of Lyme disease