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The minor A-allele of SELENOF rs5859 was associated with a significantly higher incidence of KBD 70

The recent demonstration of the importance of oxidative stress in osteoarthritis places the use of intra-articular antioxidants, namely glutathione and its precursor, as an important interventional strategy for both joint preparation for biologic therapies as well as a powerful ally in viscosupplementation

The suppression of mitochondrial ROS generation in macrophages effectively curtails inflammasome activation (165)

Zudem ist Glutathion im Serum instabil

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