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However, genetic loss of GCN2 or inhibition of GCN2 with GCN2-IN-6 did not influence the outcome of pairwise AA dropouts and -Met rescue of threonine deprivationassociated cell death (Fig S6AC)

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In addition to its role in pain, Substance P has been implicated in several other biological processes, including the regulation of blood pressure, the regulation of the immune response, and the regulation of gut motility