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doi: 10.3390/ijms25147943

10.1164/ajrccm.163.6.2009116 9

10.3390/ijms23020662 108

In addition, changes in the catecholamine branch of tyrosine metabolism like increase in VMA and decrease in MHPG, and changes in the end products of purine pathway, such as decreases in XAN and HX, were identified in the MDD patients after drug exposure

Animals Male SpragueDawley (SD) rats used for the spinal nerve ligation (SNL) (5 weeks old) and formalin tests (8 weeks old) were purchased from Koatech Co., Ltd