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coli WT + light group dropped to 36.5% 2.5% of the initial level, indicating that ROS accumulation disrupted metabolism and impaired ATP synthesis

401 DCs DCs, as APCs, are critical for immune responses in contact with commensal microbiota

Rigorous studies are needed to elucidate the precise mechanisms by which ferritin modulates ferroptosis and CSC resistance

The accumulation of oxidized lipids, such as prostaglandin E2 (PGE2), fatty acid transport protein 2 (FATP2), and arachidonic acid, also contributes to MDSC-mediated immune suppression through oxidative stress [460]

However, it is not considered an essential nutrient because the body can make it from the amino acids lysine and methionine