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By functioning as a precursor for glutamine, -KG also takes a center position in maintaining the redox balance of the cell

Biomaterials 294 , 122025 (2023)

The accumulation of C16:0 ceramide also might alter the balance between sphingolipids, phospholipids, and other membrane constituents, leading to increased membrane rigidity and permeability (Fucho et al., 2017)