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In therapy, Panobinostat induces CD38 upregulation, thereby improving the anti-myeloma effects of Daratumumab ( 2.1.1.3 JAK-STAT signaling pathway The JAK-STAT pathway can influence CD38 regulation through its signaling activities

Anti-CD38 single domain antibodies as new therapeutic agents Today, while daratumumab and isatuximab have become integral components of first-line MM treatment regimens, some limitations have emerged in the use of mAbs as agents

adequate water intake to support CSF and endolymph dynamics