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MTHFR Gene Mutation Causes There is no specific cause of MTHFR gene mutations

It wasn't far about 50 feet from my desk to an editor's desk but people in the newsroom stopped what they were doing and gawked

However, its still possible to be deficient, especially if you: have certain medical conditions, such as pernicious anemia and Crohns disease take certain medications, such as proton pump inhibitors follow a strict vegan or vegetarian diet The following symptoms may signal youre not getting enough B vitamins: fatigue weakness dyspnea (shortness of breath) heart palpitations loss of appetite headaches mouth ulcers swollen tongue irritability depression indigestion diarrhea cognitive changes, such as confusion and memory problems Speak with a healthcare professional if you experience any of these symptoms

Orforglipron is another drug in the pipeline, demonstrating activity only as a GLP-1 agonist

Extrapolating from B12 supplementation trials of non-vegans to determine the needs of vegans is complicated by the fact that a high percentage of any small dose of B12 is absorbed and omnivores are normally receiving numerous small doses throughout the day