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In this study, participants either were given Module 1 or 2

The disulfide bonds in certain proteins are oxidized by ROS which can affect their activity, especially in the tyrosine phosphatases superfamily [25]

Bhattacharya SK, Satyan KS, Chakrabarti A (1997) Anxiogenic action of caffeine: an experimental study in rats

Moreover, spermidine inhibits histone acetyltransferase p300 (EP300), a protein that suppresses autophagy, thereby enabling the activation of autophagy-related genes (Atg) (Reference Madeo, Carmona-Gutierrez and Kepp18)