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National Institute of Drug Abuse

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Other population-based studies have found that ~7% of ASD patients had an OXPHOS dysfunction [70, 72]

Functional fatty-acid oxidation testing demonstrated elevations in the short-chain fatty-acid D3-C4 (Figures 5e and f)

Thus, unlike the DR-1 element positioned close to the SHBG transcription start site, and which functions through interactions with COUP-TF and HNF-4 as the main transcriptional on-off switch in the liver 8 , the upstream DR-1 element that interacts with CAR may represent a fine-tuner that responds to a number of related NHRs many of which regulate responses to metabolic disturbances during disease or after exposure to drugs or environmental xenobiotic ligands