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10.1016/j.biotechadv.2020.107545 46 LpezC

There is a growing number of instances where antibiotic treatment is not practical, leading to the development of persistent systemic infections in humans

In the case of progressive cancerization, the cumulative probability over time for a given cell of having accumulated the necessary complementary events and the consequent hallmarks will increase, along with the growth of cancer incidence with age [104]

Increasing antioxidant intake has been shown to deplete OS, accordingly, creating an energy crisis for preneoplastic cells, resulting in suppression of cell growth and activation of cell death pathways to impart chemopreventive effect during cancer progression pathway [279]