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Monitored substances are tracked for use patterns in competitive athletes but are not prohibited under the World Anti-Doping Code by virtue of monitoring alone

Early research shows that MOTS-c may improve insulin sensitivity, support fat loss, boost exercise capacity, reduce inflammation, and help slow age-related muscle loss

Furthermore, the co-infusion of leptin and insulin results in an increase in TH staining, inguinal WAT browning and energy expenditure (Dodd et al., 2015), showing that both molecules can act synergistically in the CNS

Regueiro et al., 2023)

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