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Therefore, impaired renal function would likely impact both plasma and urine PK of pudexacianinium: compared with those without renal impairment, theoretically plasma concentration would be higher, urinary excretion would be lower, and urine concentration would be lower in participants with renal impairment

For any study to hold weight the more data, the more likely the results are true

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10.1523/jneurosci.3906-03.2004 110 SambandanS.SauerJ

This range harmonizes effectiveness, inducing collagen, decorin, and glycosaminoglycan production, with tolerability